Description

6-Bromo-3-(4-Piperidinyl)-1H-Indole CAS NO 959236-51-2 is a high-purity, advanced pharmaceutical intermediate featuring a versatile indole-piperidine scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates targeting central nervous system and oncological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Kinase Inhibitor Development: Used in the research and development of selective kinase inhibitors for oncology applications.
• GPCR Ligand Synthesis: Building block for creating ligands targeting G-protein-coupled receptors (GPCRs).
• Chemical Biology Probes: Serves as a starting material for developing tool compounds and molecular probes.
• Process Chemistry & Scale-up: Supplied in development and pilot-scale quantities for route optimization and cGMP manufacturing.

Basic Information

Product Name	6-Bromo-3-(4-Piperidinyl)-1H-Indole
CAS No.	959236-51-2
Molecular Formula	C13H15BrN2
Molecular Weight	279.18 g/mol
Synonyms	6-Bromo-3-(4-piperidinyl)-1H-indole; 6-Bromo-3-piperidin-4-yl-1H-indole; 1H-Indole, 6-bromo-3-(4-piperidinyl)-; 3-(Piperidin-4-yl)-6-bromo-1H-indole; 6-Bromo-3-(piperidin-4-yl)indole; 6-Bromo-3-(4-piperidyl)indole; 959236-51-2; 6-Br-3-(4-Pip)-1H-Indole
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-(4-Piperidinyl)-1H-Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.