Description

5-Trifluoromethyl-3-(4-Piperidinyl)-1H-Indole is a high-value, heterocyclic organic compound featuring a unique indole core substituted with a trifluoromethyl group and a piperidine moiety. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel bioactive molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Serves as a privileged scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Used in the research and development of new active ingredients for crop protection products.
• Fine Chemical Synthesis: Employed as a specialized building block for creating complex, fluorinated organic molecules in custom synthesis projects.
• Biochemical Tool Compound: Potential use in developing probes for studying biological pathways and enzyme interactions.

Basic Information

Product Name	5-Trifluoromethyl-3-(4-Piperidinyl)-1H-Indole
CAS No.	959236-45-4
Molecular Formula	C14H15F3N2
Molecular Weight	268.28 g/mol
Synonyms	3-(4-Piperidinyl)-5-(trifluoromethyl)-1H-indole; 5-(Trifluoromethyl)-3-(4-piperidinyl)indole; 1H-Indole, 5-(trifluoromethyl)-3-(4-piperidinyl)-; 3-(Piperidin-4-yl)-5-(trifluoromethyl)-1H-indole; 5-Trifluoromethyl-3-piperidin-4-yl-1H-indole
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.