Description

2-(4-(Trifluoromethyl)-1H-Indol-3-Yl)Ethanamine is a high-value, functionalized indole derivative featuring a reactive primary amine group and a trifluoromethyl substituent. This unique molecular architecture makes it a critical pharmaceutical intermediate and a versatile building block for advanced organic synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and material science sectors for developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of small molecule drugs, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Building block for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profile.
• Ligand & Catalyst Development: Used to create novel ligands for catalysis and metal-organic frameworks (MOFs) due to its amine functionality and aromatic indole core.
• Fluorinated Compound Synthesis: Serves as a source of the trifluoromethyl group for introducing fluorine atoms into target molecules to improve metabolic stability and lipophilicity.
• Bioconjugation & Probe Chemistry: The primary amine group enables conjugation to biomolecules, peptides, or fluorescent tags for diagnostic and research applications.
• Material Science: Monomer or additive for specialty polymers and advanced organic electronic materials.

Basic Information

Item	Details
Product Name	2-(4-(Trifluoromethyl)-1H-Indol-3-Yl)Ethanamine
CAS No.	959236-33-0
Molecular Formula	C11H11F3N2
Molecular Weight	228.21 g/mol
Synonyms	2-[4-(Trifluoromethyl)-1H-indol-3-yl]ethan-1-amine; 3-(2-Aminoethyl)-4-(trifluoromethyl)-1H-indole; 4-(Trifluoromethyl)tryptamine; 4-TFMT; 2-(4-Trifluoromethyl-1H-indol-3-yl)ethylamine; α-Methyl-4-(trifluoromethyl)tryptamine (common misnomer); 4-CF3-Tryptamine; 959236-33-0
EINECS	Contact for details

Quality Control

Our 2-(4-(Trifluoromethyl)-1H-Indol-3-Yl)Ethanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.