Description

1-Boc-6-Cyano-2,3-Dihydro-Indole is a high-purity, protected indole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and bioactive compounds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for its synthetic versatility and reliability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core structure.
• Fine Chemical Synthesis: Serves as a versatile scaffold for creating complex molecules in custom synthesis and process development.
• Academic & R&D: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.
• Peptidomimetics: The protected indole and cyano groups make it useful for constructing non-peptide bioactive mimics.

Basic Information

Product Name	1-Boc-6-Cyano-2,3-Dihydro-Indole
CAS No.	959236-08-9
Molecular Formula	C14H16N2O2
Molecular Weight	244.29 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-6-cyano-2,3-dihydro-1H-indole; 6-Cyano-2,3-dihydro-1H-indole-1-carboxylic acid tert-butyl ester; tert-Butyl 6-cyano-2,3-dihydro-1H-indole-1-carboxylate; 1-Boc-6-cyanoindoline; Boc-6-CN-indoline; 959236-08-9; 1-N-Boc-6-cyanoindoline
EINECS	Contact for details

Quality Control

Our 1-Boc-6-Cyano-2,3-Dihydro-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.