Description

1H-Indole,2,3-Dihydro-6-(Trifluoromethoxy)- is a specialized indole derivative, a crucial fluorinated building block in advanced organic synthesis. Its molecular structure, featuring both the indoline core and a trifluoromethoxy substituent, makes it a high-value intermediate for creating novel compounds with enhanced biological activity and physicochemical properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethoxy group can improve metabolic stability and lipophilicity.
• Material Science Research: Serves as a precursor for functional organic materials, including organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	1H-Indole,2,3-Dihydro-6-(Trifluoromethoxy)-
CAS No.	959235-95-1
Molecular Formula	C9H8F3NO
Molecular Weight	203.16 g/mol
Synonyms	6-(Trifluoromethoxy)-2,3-dihydro-1H-indole; 6-(Trifluoromethoxy)indoline; 2,3-Dihydro-6-(trifluoromethoxy)-1H-indole; 6-Trifluoromethoxyindoline; 1H-Indole, 2,3-dihydro-6-(trifluoromethoxy)-; 959235-95-1; 6-OCF3-Indoline
EINECS	Contact for details

Quality Control

Our 1H-Indole,2,3-Dihydro-6-(Trifluoromethoxy)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We adhere to cGMP principles where applicable to ensure consistent batch-to-batch reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.