Description

4-Methylphenyl 3-o-Benzyl-4,6-o-Benzylidene-1-Thio-β-D-Mannopyranoside is a sophisticated, protected thioglycoside building block of significant interest in synthetic carbohydrate chemistry. Its core value lies in its role as a key synthetic intermediate for the controlled construction of complex oligosaccharides and glycoconjugates. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing novel therapeutics, vaccines, and diagnostic tools that target carbohydrate-mediated biological processes. The compound is supplied with CAS number 959153-42-5.

Application

• Glycoscience Research: A critical precursor for the stereoselective synthesis of mannose-containing oligosaccharides and glycans.
• Pharmaceutical Intermediates: Used in the development of active pharmaceutical ingredients (APIs) for drugs targeting infections, cancer, and inflammatory diseases.
• Glycoconjugate Vaccine Development: Serves as a building block for creating carbohydrate antigens conjugated to carrier proteins.
• Glycoprotein Mimetics: Enables the synthesis of stable glycomimetics for studying protein-carbohydrate interactions.
• Chemical Biology Probes: Utilized to create labeled or modified sugars for tracking metabolic pathways and biological recognition events.
• Process Development: Supports scale-up and optimization of glycosylation reactions in pilot and commercial manufacturing.

Basic Information

Product Name	4-Methylphenyl 3-o-Benzyl-4,6-o-Benzylidene-1-Thio-β-D-Mannopyranoside
CAS No.	959153-42-5
Molecular Formula	C27H28O5S
Molecular Weight	464.58 g/mol
Synonyms	p-Tolyl 3-O-Benzyl-4,6-O-benzylidene-1-thio-β-D-mannopyranoside; 1-Thio-β-D-mannopyranoside, 4-methylphenyl 3-O-benzyl-4,6-O-(phenylmethylene)-; 4-Methylphenyl 3-O-benzyl-4,6-O-benzylidene-1-thio-β-D-mannopyranoside; Protected Thiomannoside; Benzylidene-protected Thioglycoside Donor
EINECS	Contact for details

Quality Control

This high-value synthetic intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system is designed to support GMP-for-intermediate and research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.