Description

Phosphonic Acid, p-?Ethyl-?, Methyl Trimethylsilyl Ester is a specialized organosilicon-protected phosphonate derivative, identified by CAS NO 959070-88-3. This compound is a valuable synthetic intermediate, prized for its role in introducing phosphonate functional groups into complex molecules while offering enhanced stability and solubility in organic media. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, catalyst development, and the synthesis of novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting phosphate-mediated biological pathways.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, plant growth regulators, and other crop protection agents.
• Ligand and Catalyst Preparation: Serves as a precursor for phosphonate-based ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of flame retardants, corrosion inhibitors, and specialty polymers.
• Organic Synthesis Reagent: Utilized in Horner-Wadsworth-Emmons (HWE) olefination and other carbon-carbon bond-forming reactions under mild conditions.
• Chemical Biology Probes: Acts as a stable phosphonate analog for studying enzyme mechanisms and metabolic pathways.

Basic Information

Product Name	Phosphonic Acid, p-?Ethyl-?, Methyl Trimethylsilyl Ester
CAS No.	959070-88-3
Molecular Formula	C8H21O3PSi2
Molecular Weight	252.39 g/mol
Synonyms	Methyl (p-Ethylphenyl)phosphonate Trimethylsilyl Ester; [(4-Ethylphenyl)methyl-phosphonato]trimethylsilane; Trimethylsilyl Methyl (4-Ethylphenyl)phosphonate; Phosphonic acid, P-(4-ethylphenyl)-, methyl ester, 2-trimethylsilyl ester; p-Ethylbenzylphosphonic Acid Methyl Trimethylsilyl Ester
EINECS	Contact for details

Quality Control

Our production of Phosphonic Acid, p-?Ethyl-?, Methyl Trimethylsilyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized by NMR (1H, 13C, 31P), GC-MS, and HPLC analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting cGMP and ISO 9001 compliant workflows for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.