Description

1,1,1-Trifluoro-3-Pyrrolidin-1-Ylpropan-2-Ol is a specialized fluorinated pyrrolidine derivative, a high-value building block in advanced organic synthesis. Its unique structure, featuring both a trifluoromethyl group and a pyrrolidine moiety, makes it a critical intermediate for creating compounds with enhanced biological activity and physicochemical properties. This chemical is essential for research and development in the pharmaceutical and agrochemical sectors, where it is used to modulate the potency, metabolic stability, and lipophilicity of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the fluorine atoms can improve efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced materials with specific surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chiral ligands and catalysts for asymmetric synthesis.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring new fluorination methodologies and the effects of fluorine substitution.
• Diagnostic Agent Development: Potential use as a building block for positron emission tomography (PET) tracers and other imaging agents.

Basic Information

Item	Detail
Product Name	1,1,1-Trifluoro-3-Pyrrolidin-1-Ylpropan-2-Ol
CAS No.	959045-77-3
Molecular Formula	C7H12F3NO
Molecular Weight	183.17 g/mol
Synonyms	2-Propanol, 1,1,1-trifluoro-3-(1-pyrrolidinyl)-; 1,1,1-Trifluoro-3-(pyrrolidin-1-yl)propan-2-ol; 3-(Pyrrolidin-1-yl)-1,1,1-trifluoropropan-2-ol; 1,1,1-Trifluoro-3-pyrrolidin-1-ylpropan-2-ol; TFPP; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1,1,1-Trifluoro-3-Pyrrolidin-1-Ylpropan-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and cGMP intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong bases. Due to its fluoride/strong alkali chemical properties, ensure proper segregation in storage areas.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.