Description

3-Hexyn-1-Amine, N,N,2,2-Tetramethyl- is a specialized alkyne-functionalized amine building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a terminal alkyne and a sterically hindered tertiary amine, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for applications such as click chemistry, ligand synthesis, and the development of novel polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of new active pharmaceutical ingredients (APIs), particularly for click chemistry-based bioconjugation and probe synthesis.
• Agrochemical Research: Used in the synthesis of novel crop protection agents and herbicides, leveraging its alkyne group for modular compound libraries.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands in transition metal catalysis and organocatalysis.
• Polymer and Material Science: Incorporated into specialty monomers for the production of functional polymers with tailored properties via alkyne-azide cycloaddition.
• Chemical Biology: Employed in the synthesis of molecular probes and tags for labeling biomolecules in diagnostic and research applications.
• Organic Synthesis Building Block: Provides a versatile handle for further functionalization through reactions at the amine or alkyne groups.

Basic Information

Product Name	3-Hexyn-1-Amine, N,N,2,2-Tetramethyl-
CAS No.	959005-78-8
Molecular Formula	C10H19N
Molecular Weight	153.26 g/mol
Synonyms	N,N,2,2-Tetramethyl-3-hexyn-1-amine; 3-Hexyn-1-amine, N,N,2,2-tetramethyl-; 2,2,N,N-Tetramethylhex-3-yn-1-amine; Tetramethyl-3-hexynylamine; 3-Hexynylamine, N,N,2,2-tetramethyl-; N,N,2,2-Tetramethylhex-3-yn-1-amine
EINECS	Contact for details

Quality Control

Our 3-Hexyn-1-Amine, N,N,2,2-Tetramethyl- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, identity (IR, NMR), and impurity profiles are available upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain purity and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.