Description

([2-Fluoro-5-(Trifluoromethyl)Phenyl]Methyl)(Methyl)Amine is a high-value fluorinated aromatic amine building block, distinguished by its unique trifluoromethyl and fluorine substituents. This compound is essential for introducing lipophilicity, metabolic stability, and electronic modulation into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in CNS, oncology, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine motifs enhance bioactivity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands in catalysis and as a building block for functionalized materials.
• Organic Electronic Materials: Employed in the synthesis of charge-transport materials and fluorophores for OLEDs and other optoelectronic applications.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological mechanisms and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	([2-Fluoro-5-(Trifluoromethyl)Phenyl]Methyl)(Methyl)Amine
CAS No.	958863-66-6
Molecular Formula	C10H9F4N
Molecular Weight	219.18 g/mol
Synonyms	N-Methyl-1-[2-fluoro-5-(trifluoromethyl)phenyl]methanamine; 1-(2-Fluoro-5-(trifluoromethyl)phenyl)-N-methylmethanamine; N-Methyl(2-fluoro-5-(trifluoromethyl)benzyl)amine; (2-Fluoro-α-methyl-5-(trifluoromethyl)benzenemethanamine; Benzenemethanamine, 2-fluoro-α-methyl-5-(trifluoromethyl)-; α-Methyl-2-fluoro-5-(trifluoromethyl)benzylamine
EINECS	Contact for details

Quality Control

Our ([2-Fluoro-5-(Trifluoromethyl)Phenyl]Methyl)(Methyl)Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with each shipment. We support development and commercial projects with material produced to meet relevant ISO, ICH Q7, and customer-specific quality guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials such as strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.