Description

2-Pyridinecarboxamide, n-[1-(2,4-Difluorophenyl)-4,5,6,7-Tetrahydro-1H-Indazol-4-Yl]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Medicinal Chemistry Research: Used as a scaffold or core structure for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of drug candidates.
• Biochemical Tool Compound: Serves as a reference standard or a probe molecule in biochemical assays to study specific enzyme inhibition or receptor modulation.
• Process Development & Scale-up: Employed in the development and optimization of robust, scalable synthetic routes for GMP (Good Manufacturing Practice) production.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis for client-sponsored drug development projects.

Basic Information

Product Name	2-Pyridinecarboxamide, n-[1-(2,4-Difluorophenyl)-4,5,6,7-Tetrahydro-1H-Indazol-4-Yl]-
CAS No.	958842-64-3
Molecular Formula	C19H16F2N4O
Molecular Weight	354.36 g/mol
Synonyms	N-[1-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-1H-indazol-4-yl]pyridine-2-carboxamide; 958842-64-3; UNII-9J8B5QY9VD; 9J8B5QY9VD; CHEMBL3186662; AKOS015915991; ZINC000003869007; SCHEMBL15427497
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing comprehensive analytical results, including HPLC purity, are provided with every shipment. We support our clients' regulatory needs with traceable documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.