Description

(5-Amino-2-Chlorophenyl)Boronic Acid is a high-purity, functionalized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, where the boronic acid group enables Suzuki-Miyaura cross-coupling reactions, and the aromatic amine provides a versatile handle for further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules in drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen and amine substituents for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the production of advanced polymers, resins, and organic electronic materials.
• Ligand for Catalysis: Can be utilized to develop novel ligands for transition metal catalysts used in asymmetric synthesis.
• Bioconjugation & Probe Development: The boronic acid moiety allows for conjugation with diols, making it useful in developing sensors, diagnostic probes, and bioconjugates.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new C-C bond formation methodologies and constructing diverse chemical libraries.

Basic Information

Product Name	(5-Amino-2-Chlorophenyl)Boronic Acid
CAS No.	958646-69-0
Molecular Formula	C6H7BClNO2
Molecular Weight	171.39 g/mol
Synonyms	2-Chloro-5-aminophenylboronic Acid; (2-Chloro-5-aminophenyl)boronic Acid; 5-Amino-2-chlorobenzeneboronic Acid; B-(5-Amino-2-chlorophenyl)boronic Acid; 2-Chloro-5-aminobenzeneboronic Acid; 958646-69-0; AKOS BRN-0769
EINECS	Contact for details

Quality Control

Our (5-Amino-2-Chlorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.