Description

1H-Indole-3-Carboxylic Acid, 4-(Aminomethyl)-5-Hydroxy-2-Methyl- is a high-purity, multi-functional indole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile building block for the development of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating innovative therapeutic agents and complex chemical libraries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic pathways.
• Biochemical Research: Used as a specialized reagent and building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a core structure for creating new plant growth regulators or bioactive agrochemicals.
• Peptide Mimetics & Conjugates: The carboxylic acid and aminomethyl groups allow for facile conjugation, making it useful in designing peptide analogs and bioconjugates.
• Chemical Library Synthesis: Employed in combinatorial chemistry and high-throughput screening for the discovery of new lead compounds.
• Material Science Research: Potential monomer or functional additive in the development of specialized polymers with unique optical or electronic properties.

Basic Information

Item	Detail
Product Name	1H-Indole-3-Carboxylic Acid, 4-(Aminomethyl)-5-Hydroxy-2-Methyl-
CAS No.	958644-81-0
Molecular Formula	C11H12N2O3
Molecular Weight	220.23 g/mol
Synonyms	4-(Aminomethyl)-5-hydroxy-2-methyl-1H-indole-3-carboxylic acid; 5-Hydroxy-4-(aminomethyl)-2-methyl-1H-indole-3-carboxylic acid; 2-Methyl-4-aminomethyl-5-hydroxyindole-3-carboxylic acid; AMHICA; 4-(Aminomethyl)-5-hydroxy-2-methylindole-3-carboxylic acid; (4-Aminomethyl-5-hydroxy-2-methyl-1H-indol-3-yl)-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of our 1H-Indole-3-Carboxylic Acid, 4-(Aminomethyl)-5-Hydroxy-2-Methyl- is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.