Description

4-(3,4,4-Trifluoro-But-3-En-1-Yl-Thio)-1-Bromobenzene is a high-purity, specialized organofluorine building block designed for advanced chemical synthesis. This compound is valued for its unique trifluoroalkene and bromoaryl functional groups, which enable precise molecular construction in complex organic frameworks. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atoms and reactive sites contribute to improved efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or intermediate in the creation of specialty polymers and advanced materials with specific electronic or surface properties.
• Cross-Coupling Reactions: The bromobenzene moiety makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research focused on incorporating trifluoroalkene units into target molecules.
• Ligand and Catalyst Development: Used to synthesize novel chelating ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	4-(3,4,4-Trifluoro-But-3-En-1-Yl-Thio)-1-Bromobenzene
CAS No.	958452-01-2
Molecular Formula	C10H8BrF3S
Molecular Weight	297.14 g/mol
Synonyms	1-Bromo-4-[(3,4,4-trifluorobut-3-en-1-yl)sulfanyl]benzene; 4-[(3,4,4-Trifluorobut-3-en-1-yl)thio]bromobenzene; p-Bromophenyl 3,4,4-trifluorobut-3-enyl sulfide; 4-Bromophenyl 3,4,4-trifluorobut-3-enyl thioether; 958452-01-2; CAS 958452-01-2
EINECS	Contact for details

Quality Control

Our 4-(3,4,4-Trifluoro-But-3-En-1-Yl-Thio)-1-Bromobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.