Description

(S)-1-Phenylethanethiol CAS NO 33877-11-1 is a high-purity chiral thiol compound, serving as a versatile and critical building block in asymmetric synthesis. Its value lies in its ability to act as a chiral auxiliary or ligand, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors who require precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) requiring specific (S)-configuration.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for transition metal catalysis, facilitating enantioselective reactions.
• Chiral Derivatizing Agent: Employed for the resolution of racemic mixtures or for analytical purposes to determine enantiomeric purity via chromatography.
• Fine Chemical Synthesis: A building block for creating complex molecules with sulfur-containing stereocenters in agrochemicals and specialty chemicals.
• Material Science Research: Investigated for incorporation into polymers or surfaces to impart chiral properties or specific molecular recognition.

Basic Information

Product Name	(S)-1-Phenylethanethiol
CAS No.	33877-11-1
Molecular Formula	C8H10S
Molecular Weight	138.23 g/mol
Synonyms	(S)-(-)-1-Phenylethanethiol; (S)-α-Methylbenzyl mercaptan; (S)-1-Phenylethyl mercaptan; (S)-(-)-α-Methylbenzylthiol; (S)-1-Phenylethylthiol; (S)-(-)-1-Phenylethylthiol; (S)-Phenylethanethiol; (S)-α-Toluenethiol
EINECS	Contact for details

Quality Control

Our (S)-1-Phenylethanethiol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC or GC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.