Description

1-(2-Bromoethyl)-3,5-Difluorobenzene is a versatile and high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its reactive bromoethyl and difluorophenyl moieties, which enable precise molecular construction in complex chemical environments. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a difluorobenzene scaffold for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms contribute to product efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, contributing to improved performance and stability.
• Cross-Coupling Reactions: The bromoethyl group acts as an effective handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Functional Polymer Monomer: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, or optical properties.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry in both academic and industrial R&D settings for exploring new chemical entities.

Basic Information

Item	Details
Product Name	1-(2-Bromoethyl)-3,5-Difluorobenzene
CAS No.	958027-90-2
Molecular Formula	C8H7BrF2
Molecular Weight	221.04 g/mol
Synonyms	3,5-Difluoro-1-(2-bromoethyl)benzene; 2-(3,5-Difluorophenyl)ethyl Bromide; 1-Bromo-2-(3,5-difluorophenyl)ethane; (3,5-Difluorophenyl)ethyl Bromide; 2-Bromoethyl-3,5-difluorobenzene; 958027-90-2; 3,5-Difluorophenethyl Bromide
EINECS	Contact for details

Quality Control

Every batch of 1-(2-Bromoethyl)-3,5-Difluorobenzene is manufactured and tested under a strict quality management system. We ensure compliance with rigorous internal specifications, which are aligned with industry best practices for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture ingress and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.