Description

1-Bromo-3-Fluoropropane is a versatile halogenated alkane building block of significant importance in advanced organic synthesis. Its bifunctional nature, featuring both bromine and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to introduce fluorinated alkyl chains or create novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and prodrugs, leveraging the metabolic stability often imparted by fluorine atoms.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the fluorine moiety can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated components in electronic display and lighting technologies.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, altering surface properties, hydrophobicity, and chemical resistance.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form carbon-carbon bonds.
• Nucleophilic Substitution Substrate: The bromine atom is an excellent leaving group for reactions with a wide range of nucleophiles, enabling chain elongation and functional group interconversion.

Basic Information

Item	Details
Product Name	1-Bromo-3-Fluoropropane
CAS No.	352-91-0
Molecular Formula	C3H6BrF
Molecular Weight	141.98 g/mol
Synonyms	3-Fluoropropyl bromide; 3-Fluoro-1-bromopropane; 1-Bromo-3-fluoropropane; 3-Bromopropyl fluoride; Fluoropropyl bromide; Propane, 1-bromo-3-fluoro-; (3-Fluoropropyl)bromide
EINECS	206-525-6

Quality Control

Our 1-Bromo-3-Fluoropropane is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and maintain purity. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	1.45 - 1.50 g/mL
Refractive Index (n20D)	1.440 - 1.450

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.