Description

tert-Butyl 3-Cyclohexyl-2-(2-Formyl-4-Methoxyphenyl)-1H-Indole-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex indole-based molecular architecture. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in oncology and central nervous system (CNS) disease research.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic compounds due to its reactive formyl and ester functional groups.
• Drug Discovery Programs: Serves as a starting material or intermediate in high-throughput screening libraries and lead optimization processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Used in university and institutional labs for studies in synthetic methodology and new reaction development.

Basic Information

Product Name	tert-Butyl 3-Cyclohexyl-2-(2-Formyl-4-Methoxyphenyl)-1H-Indole-6-Carboxylate
CAS No.	958002-18-1
Molecular Formula	C27H31NO4
Molecular Weight	433.54 g/mol
Synonyms	tert-Butyl 3-cyclohexyl-2-(2-formyl-4-methoxyphenyl)-1H-indole-6-carboxylate; 6-Carboxy-3-cyclohexyl-2-(2-formyl-4-methoxyphenyl)indole tert-butyl ester; 1H-Indole-6-carboxylic acid, 3-cyclohexyl-2-(2-formyl-4-methoxyphenyl)-, 1,1-dimethylethyl ester; 958002-18-1; tert-Butyl 3-cyclohexyl-2-(2-formyl-4-methoxyphenyl)indole-6-carboxylate; 3-Cyclohexyl-2-(2-formyl-4-methoxyphenyl)-1H-indole-6-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Cyclohexyl-2-(2-Formyl-4-Methoxyphenyl)-1H-Indole-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.