Description

B-(1-Methyl-1H-Imidazol-4-Yl)-Boronic Acid is a specialized organoboron compound featuring a methylated imidazole core, serving as a crucial building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas, including kinase inhibitors and antiviral agents.
• Agrochemical Research: Used to create novel heterocyclic compounds for the development of new pesticides and herbicides with improved efficacy.
• Material Science: Building block for the synthesis of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) and components for organic light-emitting diodes (OLEDs).
• Suzuki-Miyaura Cross-Coupling: A pivotal boronic acid reagent for palladium-catalyzed carbon-carbon bond formation, facilitating the synthesis of biaryl and heterobiaryl structures.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and activity-based protein profiling (ABPP) agents due to its reactive boronic acid handle.
• Catalyst & Ligand Development: Serves as a precursor for creating novel N-heterocyclic carbene (NHC) ligands and other catalytic systems.

Basic Information

Product Name	B-(1-Methyl-1H-Imidazol-4-Yl)-Boronic Acid
CAS No.	957720-01-3
Molecular Formula	C4H7BN2O2
Molecular Weight	125.93 g/mol
Synonyms	(1-Methyl-1H-imidazol-4-yl)boronic acid; 4-Borono-1-methyl-1H-imidazole; 1-Methyl-4-imidazoleboronic acid; 1-Methyl-1H-imidazole-4-boronic acid; B-(1-Methylimidazol-4-yl)boronic acid; 4-(Dihydroxyboryl)-1-methyl-1H-imidazole; 1-Methyl-4-imidazolylboronic acid; 1-Methyl-4-boronoimidazole
EINECS	Contact for details

Quality Control

Our B-(1-Methyl-1H-Imidazol-4-Yl)-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding research and scale-up applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.