Description

Disiamylborane is a highly reactive organoboron compound, specifically a dialkylborane, widely used as a selective hydroborating agent in organic synthesis. Its core value lies in enabling the stereoselective and regioselective synthesis of complex organic molecules, a critical process for advanced chemical manufacturing. This reagent is essential for R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries, where precise chemical transformations are paramount.

Application

• Selective Hydroboration of Alkenes and Alkynes: Key for the controlled synthesis of organoboranes as versatile synthetic intermediates.
• Pharmaceutical Intermediate Synthesis: Used in the production of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Manufacturing: Employed in creating complex molecules for crop protection agents and herbicides.
• Fine Chemical and Material Science Research: Facilitates the development of novel polymers, liquid crystals, and electronic materials.
• Asymmetric Synthesis: Valuable in chiral synthesis pathways for producing enantiomerically pure compounds.
• Cross-Coupling Reaction Precursors: Serves as a precursor to boronic esters used in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	Disiamylborane
CAS No.	1069-54-1
Molecular Formula	C10H23B
Molecular Weight	154.10 g/mol
Synonyms	Bis(3-methyl-2-butyl)borane; Di-3-methyl-2-butylborane; Disiamylborane solution; Sia2BH; Disiamylborane (typically as a solution in THF or other ethers); Borane, bis(1,2-dimethylpropyl)-; (1,2-Dimethylpropyl)borane dimer (related form)
EINECS	Contact for details

Quality Control

Our Disiamylborane is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is characterized by NMR spectroscopy to confirm identity and assay purity. Certificates of Analysis (COA) detailing specific analytical results are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and easily oxidized nature, this product must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions. The storage area should be cool, dry, and well-ventilated, away from heat, sparks, and open flames. Always refer to the specific Safety Data Sheet (SDS) for the exact grade and solvent system supplied.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (NMR)	Conforms to structure
Assay (by Titration)	≥ 0.5 M in specified solvent (e.g., THF)
Purity (NMR)	≥ 95% (of active borane species)
Solvent	Specified (e.g., Tetrahydrofuran, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.