Description

4-(Hydroxymethyl)-2,6-Dimethylphenylboronic Acid is a high-purity boronic acid derivative featuring a hydroxymethyl functional group, making it a versatile building block for Suzuki-Miyaura cross-coupling reactions. This compound is critical for the efficient synthesis of complex biaryl structures found in advanced pharmaceutical intermediates and organic electronic materials. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce functionalized aromatic units into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science: Used in the development of organic light-emitting diodes (OLEDs), conductive polymers, and liquid crystal materials.
• Chemical Research: Essential reagent in academic and industrial laboratories for constructing complex molecular architectures and exploring new catalytic methodologies.
• Peptide Modification: Potential use in bioconjugation chemistry for labeling biomolecules.

Basic Information

Product Name	4-(Hydroxymethyl)-2,6-Dimethylphenylboronic Acid
CAS No.	2121513-77-5
Molecular Formula	C9H13BO3
Molecular Weight	179.01 g/mol
Synonyms	(4-(Hydroxymethyl)-2,6-dimethylphenyl)boronic acid; 2,6-Dimethyl-4-(hydroxymethyl)benzeneboronic acid; 4-(Hydroxymethyl)-2,6-dimethylbenzeneboronic acid; B-[4-(Hydroxymethyl)-2,6-dimethylphenyl]boronic acid
EINECS	Contact for details

Quality Control

Our 4-(Hydroxymethyl)-2,6-Dimethylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.