Description

Chloro(Dimethylamino)Phenylborane is a versatile organoboron reagent featuring a chloro and a dimethylamino ligand on the boron center. This compound is valued for its dual reactivity, serving as a key intermediate in the synthesis of complex boronic esters and other functionalized boron compounds. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for cross-coupling reactions and catalyst development.

Application

• Pharmaceutical Intermediate: A crucial building block in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions for constructing biaryl motifs found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific boron-containing molecular architectures.
• Materials Science: Serves as a precursor for boron-doped organic semiconductors, liquid crystals, and other functional materials.
• Catalyst Ligand Precursor: Can be transformed into novel N,B-chelating ligands for transition metal catalysis.
• Organic Synthesis Reagent: Employed in hydroboration reactions and as a protected boronic acid equivalent in multi-step synthetic sequences.
• Research & Development: A valuable tool for academic and industrial R&D laboratories exploring new methodologies in organometallic and boron chemistry.

Basic Information

Product Name	Chloro(Dimethylamino)Phenylborane
CAS No.	1196-44-7
Molecular Formula	C8H11BClN
Molecular Weight	167.44 g/mol
Synonyms	Phenylchloro(dimethylamino)borane; (Dimethylamino)phenylchloroborane; Chloro(N,N-dimethyl)phenylboranamine; N,N-Dimethylamino(phenyl)chloroborane; B-Chloro-B-phenyl-N,N-dimethylboranamine; Dimethylaminophenylchloroborane; Phenyl(dimethylamino)chloroborane
EINECS	214-819-5

Quality Control

Our Chloro(Dimethylamino)Phenylborane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We adhere to current Good Manufacturing Practices (cGMP) where applicable. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global customer base in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.