Description

Thiazole, 4-Fluoro- is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of a fluorine atom can dramatically alter biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profile.
• Material Science Research: Serves as a precursor for developing specialty chemicals, liquid crystals, and advanced polymers with unique electronic or optical properties.
• Chemical Biology & Proteomics: Employed as a tagging reagent or a scaffold for designing molecular probes and enzyme inhibitors.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, focusing on fluorination and heterocycle chemistry.
• Custom Synthesis & Scale-Up: The starting point for contract manufacturing organizations (CMOs) to produce bespoke intermediates under cGMP or ISO standards for client projects.

Basic Information

Product Name	Thiazole, 4-Fluoro-
CAS No.	957370-37-5
Molecular Formula	C3H2FNS
Molecular Weight	103.12 g/mol
Synonyms	4-Fluorothiazole; 4-Fluoro-1,3-thiazole; 4-Fluoro-thiazole; Fluorothiazole; Thiazole, fluoro-; 1,3-Thiazole, 4-fluoro-; 4-Fluoro-1-thia-3-azacyclopenta-2,4-diene
EINECS	Contact for details

Quality Control

Every batch of 4-Fluorothiazole is produced and analyzed under strict quality management protocols. We ensure compliance with relevant industry standards for advanced intermediates. Comprehensive in-process and final release testing is performed, including identity confirmation, purity assay, and impurity profiling. A detailed Certificate of Analysis (COA) documenting all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.