Description

Carbamic Acid, n-[5-[2-(Trimethylsilyl)Ethynyl]-2-Thiazolyl]-, 1,1-Dimethylethyl Ester is a specialized organosilicon-thiazole derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring a trimethylsilyl-protected ethynyl group and a thiazole heterocycle, makes it a valuable building block for constructing complex pharmacophores and functional materials. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways where the thiazole moiety is pharmacologically active.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of advanced polymers and silicon-containing hybrid materials.
• Chemical Synthesis: Serves as a protected alkyne building block in multi-step organic synthesis, including Sonogashira and other cross-coupling reactions.
• Academic & Contract Research: Essential reagent for university laboratories and CROs (Contract Research Organizations) exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	Carbamic Acid, n-[5-[2-(Trimethylsilyl)Ethynyl]-2-Thiazolyl]-, 1,1-Dimethylethyl Ester
CAS No.	957147-21-6
Molecular Formula	C15H24N2O2SSi
Molecular Weight	324.52 g/mol
Synonyms	tert-Butyl N-[5-[(2-trimethylsilyl)ethynyl]-1,3-thiazol-2-yl]carbamate; 2-Thiazolamine, 5-[(2-trimethylsilyl)ethynyl]-, 1,1-dimethylethyl ester; 5-[(2-Trimethylsilyl)ethynyl]-1,3-thiazol-2-amine, N-Boc derivative; Boc-5-[(2-Trimethylsilyl)ethynyl]thiazol-2-ylamine; TMS-Ethynyl Thiazole Carbamate; CAS 957147-21-6; (TMS)ethynyl-thiazole Boc-carbamate
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, n-[5-[2-(Trimethylsilyl)Ethynyl]-2-Thiazolyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; therefore, containers should be kept sealed under an inert atmosphere when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.