Description

n-Boc-1H-Indole-6-Carboxylic Acid Methyl Ester is a high-purity, protected indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable building blocks for drug discovery and API synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting neurological and oncological pathways.
• Peptidomimetic Research: Used in the design and synthesis of indole-containing peptidomimetics and constrained peptides.
• Agrochemical Synthesis: Intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers and advanced organic materials.
• Academic & R&D: Fundamental reagent in university and contract research laboratories for methodological studies and novel compound library generation.
• Scale-up Process Development: Used in pilot plants and kilo labs to develop and optimize scalable synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	n-Boc-1H-Indole-6-Carboxylic Acid Methyl Ester
CAS No.	957127-83-2
Molecular Formula	C15H17NO4
Molecular Weight	275.30 g/mol
Synonyms	1H-Indole-6-carboxylic acid, 1-[(1,1-dimethylethoxy)carbonyl]-, methyl ester; Methyl 1-[(tert-butoxy)carbonyl]-1H-indole-6-carboxylate; Methyl 1-Boc-indole-6-carboxylate; 1-Boc-6-(methoxycarbonyl)indole; tert-Butyl 6-(methoxycarbonyl)-1H-indole-1-carboxylate; Boc-Indole-6-COOMe
EINECS	Contact for details

Quality Control

Our n-Boc-1H-Indole-6-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.