2-Chloro-6-Fluoro-3-Hydroxyphenylboronic Acid CAS NO 957121-07-2

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CAS No.:957121-07-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Chloro-6-Fluoro-3-Hydroxyphenylboronic Acid CAS NO 957121-07-2 is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its unique halogenated hydroxyphenyl structure, which enables precise cross-coupling reactions for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the chloro-fluoro substitution pattern contributes to biological activity and environmental stability.
Material Science Research: Employed in the creation of organic electronic materials and metal-organic frameworks (MOFs) due to its ability to form stable boronate esters.
Chemical Biology Probes: Serves as a versatile handle for bioconjugation and the development of sensors and diagnostic tools targeting specific biomolecules.
Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-fidelity boronic acid reagents.

Basic Information


Product Name	2-Chloro-6-Fluoro-3-Hydroxyphenylboronic Acid
CAS No.	957121-07-2
Molecular Formula	C6H5BClFO3
Molecular Weight	189.37 g/mol
Synonyms	(2-Chloro-6-fluoro-3-hydroxyphenyl)boronic acid; 2-Chloro-6-fluoro-3-hydroxybenzeneboronic acid; Boronic acid, B-(2-chloro-6-fluoro-3-hydroxyphenyl)-; 3-Borono-2-chloro-6-fluorophenol; 957121-07-2; 2-Chloro-6-fluorophenol-3-boronic acid; 2-Chloro-6-fluoro-3-phenolboronic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluoro-3-Hydroxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.