Description

4-(n-Naphthalen-1-Ylsulfamoyl)Phenylboronic Acid CAS NO 957120-95-5 is a specialized organoboron compound featuring a naphthalene sulfonamide moiety, making it a valuable building block in advanced organic synthesis. Its core value lies in its dual functionality, serving as both a boronic acid for Suzuki-Miyaura cross-coupling reactions and a sulfonamide group for further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in materials science for creating functional polymers and sensors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting enzymes where the sulfonamide group acts as a pharmacophore.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides by constructing diverse molecular architectures through cross-coupling.
• Material Science: Serves as a monomer or functional unit in the development of advanced polymeric materials, organic semiconductors, and sensor components.
• Chemical Biology & Proteomics: Utilized as a probe or linker in the study of protein interactions and enzyme inhibition due to its specific binding capabilities.
• Organic Synthesis Reagent: A versatile building block for constructing biaryl and complex aromatic systems via palladium-catalyzed coupling reactions.
• Ligand Development: The boronic acid and sulfonamide groups can be used to develop novel ligands for catalysis or molecular recognition applications.

Basic Information

Product Name	4-(n-Naphthalen-1-Ylsulfamoyl)Phenylboronic Acid
CAS No.	957120-95-5
Molecular Formula	C₁₆H₁₄BNO₄S
Molecular Weight	327.16 g/mol
Synonyms	4-(Naphthalen-1-ylsulfamoyl)phenylboronic Acid; 4-(1-Naphthylsulfamoyl)benzeneboronic Acid; [4-(Naphthalen-1-ylsulfamoyl)phenyl]boronic Acid; 1-Naphthalenesulfonamide, N-[4-(dihydroxyboranyl)phenyl]-; B-[4-[(1-Naphthalenylamino)sulfonyl]phenyl]boronic Acid; 4-(Naphthalene-1-sulfonylamino)phenylboronic Acid; N-(4-Boronophenyl)-1-naphthalenesulfonamide
EINECS	Contact for details

Quality Control

Our 4-(n-Naphthalen-1-Ylsulfamoyl)Phenylboronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.