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7-Bromo-1H-Indol-2-Ylboronic Acid CAS NO 957120-89-7


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CAS No.:957120-89-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

7-Bromo-1H-Indol-2-Ylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for the development of novel indole-based active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammation.
  • Agrochemical Research: Used in constructing complex heterocyclic scaffolds for new-generation herbicides, fungicides, and insecticides.
  • Material Science: Serves as a precursor for creating functional organic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
  • Chemical Biology & Proteomics: Employed in the development of molecular probes and activity-based protein profiling (ABPP) reagents due to the reactivity of the boronic acid group.
  • Academic & R&D Laboratories: A fundamental reagent for methodological development in cross-coupling chemistry and the exploration of new indole chemistry.
  • Scale-up Synthesis: Suitable for process chemistry and pilot-scale production of target molecules requiring the 7-bromoindole motif.

Basic Information

Item Detail
Product Name 7-Bromo-1H-Indol-2-Ylboronic Acid
CAS No. 957120-89-7
Molecular Formula C8H7BBrNO2
Molecular Weight 239.86 g/mol
Synonyms 7-Bromo-1H-indole-2-boronic acid; (7-Bromo-1H-indol-2-yl)boronic acid; 7-Bromoindole-2-boronic Acid; B-(7-Bromo-1H-indol-2-yl)boronic acid; 2-Borono-7-bromoindole; 7-Bromo-2-indolylboronic acid; 7-Bromo-1H-indol-2-ylboronic acid pinacol ester (common precursor); 7-Br-1H-Indole-2-B(OH)2
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Quality Control

Our 7-Bromo-1H-Indol-2-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥97.0%
Water Content (KF) ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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