Description

4-(n-Methylaminocarbonyl)Phenylboronic Acid, Propanediol Cyclic Ester is a specialized boronic acid derivative featuring a protected ester functionality. This compound is a critical building block in modern synthetic organic chemistry, particularly for Suzuki-Miyaura cross-coupling reactions, enabling the construction of complex biaryl structures. It is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific biaryl motifs.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Useful in constructing molecular probes and inhibitors for studying biological pathways and protein function.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-(n-Methylaminocarbonyl)Phenylboronic Acid, Propanediol Cyclic Ester
CAS No.	957120-71-7
Molecular Formula	C11H14BNO4
Molecular Weight	235.05 g/mol
Synonyms	4-(Methylcarbamoyl)phenylboronic acid propanediol ester; 2-Methyl-4-[4-(methylaminocarbonyl)phenyl]-1,3,2-dioxaborolane; 4-(N-Methylaminocarbonyl)benzeneboronic acid, 1,3-propanediol cyclic ester; 4-(Methylcarbamoyl)benzeneboronic acid cyclic ester with 1,3-propanediol; Boronic acid, B-[4-[(methylamino)carbonyl]phenyl]-, cyclic ester with 1,3-propanediol; CAS 957120-71-7; 4-Carbamoylphenylboronic acid propanediol ester (methyl derivative).
EINECS	Contact for details

Quality Control

Every batch of 4-(n-Methylaminocarbonyl)Phenylboronic Acid, Propanediol Cyclic Ester is manufactured and tested under a strict quality management system. We ensure high purity and consistency suitable for demanding synthetic applications. Comprehensive analytical testing, including HPLC, NMR, and elemental analysis, is performed. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.