Description

4-(2-(4-(Thpo-Methyl)-1,2,3-Triazol-1-Yl)Ethoxy)Phenylboronic Acid, Pinacol Ester is a sophisticated, high-purity boronic ester derivative, a critical intermediate in modern synthetic chemistry. Its value lies in its dual functionality, combining a protected boronic acid moiety with a triazole linker, enabling precise cross-coupling reactions and bioconjugation strategies. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced materials science who require reliable, high-quality building blocks for complex molecule assembly.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting various disease pathways.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air- and moisture-tolerant organoboron reagent for palladium-catalyzed carbon-carbon bond formation.
• Bioconjugation and Chemical Biology: The triazole moiety allows for click chemistry applications, facilitating the labeling and study of biomolecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Acts as a functional monomer or cross-linker for creating advanced polymers with specific properties.

Basic Information

Product Name	4-(2-(4-(Thpo-Methyl)-1,2,3-Triazol-1-Yl)Ethoxy)Phenylboronic Acid, Pinacol Ester
CAS No.	957120-67-1
Molecular Formula	C21H30BN3O4
Molecular Weight	399.29 g/mol
Synonyms	4-[2-[4-[(Tetrahydro-2H-pyran-2-yloxy)methyl]-1H-1,2,3-triazol-1-yl]ethoxy]benzeneboronic acid pinacol ester; 4-(2-(4-((Tetrahydro-2H-pyran-2-yloxy)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)phenylboronic acid pinacol ester; THPO-Protected Triazole Phenylboronate Ester; Pinacol 4-[2-[4-[(THP-Oxy)methyl]-1,2,3-triazol-1-yl]ethoxy]benzeneboronate
EINECS	Contact for details

Quality Control

Our production of 4-(2-(4-(Thpo-Methyl)-1,2,3-Triazol-1-Yl)Ethoxy)Phenylboronic Acid, Pinacol Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.