Description

3-Chloro-5-(Diethylcarbamoyl)Phenylboronic Acid is a high-purity, functionalized phenylboronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in the unique combination of a boronic acid group for Suzuki-Miyaura cross-coupling and a diethylcarbamoyl substituent, enabling the synthesis of complex, pharmacologically relevant molecules. This advanced intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its structural complexity for enhanced biological activity.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs or sensors, where its functional groups allow for precise structural modification.
• Cross-Coupling Reactions: Serves as a versatile boronic acid partner in palladium-catalyzed Suzuki-Miyaura cross-coupling reactions to form biaryl and heterobiaryl structures.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name	3-Chloro-5-(Diethylcarbamoyl)Phenylboronic Acid
CAS No.	957120-59-1
Molecular Formula	C11H15BClNO3
Molecular Weight	255.51 g/mol
Synonyms	[3-Chloro-5-(diethylcarbamoyl)phenyl]boronic acid; 3-Chloro-5-(N,N-diethylaminocarbonyl)benzeneboronic acid; (3-Chloro-5-(diethylcarbamoyl)phenyl)boronic acid; B-[3-Chloro-5-[(diethylamino)carbonyl]phenyl]boronic acid; 957120-59-1; 3-Chloro-5-diethylcarbamoylbenzeneboronic Acid; 3-Chloro-5-(diethylcarbamoyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(Diethylcarbamoyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (by titration)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.