Description

3-Chloro-5-(Dimethylcarbamoyl)Phenylboronic Acid is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group for Suzuki-Miyaura cross-coupling reactions with a dimethylcarbamoyl substituent that can influence the properties of the final molecule. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules for active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in constructing biaryl structures common in many therapeutic agents.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with tailored efficacy and environmental profiles.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs and sensors, due to its functional handle for polymerization.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds on a commercial scale.

Basic Information

Product Name	3-Chloro-5-(Dimethylcarbamoyl)Phenylboronic Acid
CAS No.	957120-57-9
Molecular Formula	C9H11BClNO3
Molecular Weight	227.45 g/mol
Synonyms	(3-Chloro-5-(dimethylcarbamoyl)phenyl)boronic acid; 3-Chloro-5-(N,N-dimethylcarboxamido)benzeneboronic acid; 5-Borono-3-chloro-N,N-dimethylbenzamide; B-[3-Chloro-5-[(dimethylamino)carbonyl]phenyl]boronic acid; 957120-57-9; 3-Chloro-5-(dimethylaminocarbonyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(Dimethylcarbamoyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.