Description

3-Chloro-5-(Morpholine-4-Carbonyl)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group for Suzuki-Miyaura cross-coupling reactions with a morpholine-carbonyl moiety that imparts desirable physicochemical properties. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for constructing biaryl and heterobiaryl scaffolds, a fundamental transformation in drug discovery and material science.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its structural motif for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Material Science: Potential monomer or cross-linker in the development of advanced polymeric materials with specific electronic or mechanical properties.

Basic Information

Product Name	3-Chloro-5-(Morpholine-4-Carbonyl)Phenylboronic Acid
CAS No.	957120-55-7
Molecular Formula	C11H13BClNO4
Molecular Weight	269.49 g/mol
Synonyms	[3-Chloro-5-(morpholine-4-carbonyl)phenyl]boronic acid; (3-Chloro-5-(morpholine-4-carbonyl)phenyl)boronic acid; Boronic acid, B-[3-chloro-5-(4-morpholinylcarbonyl)phenyl]-; 3-Chloro-5-(4-morpholinylcarbonyl)benzeneboronic acid; 3-Chloro-5-morpholinocarbonylphenylboronic acid; 957120-55-7; AKOS006349889; FT-0773665
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(Morpholine-4-Carbonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.