Description

3-Chloro-5-(Ethylcarbamoyl)Phenylboronic Acid is a high-purity, functionalized phenylboronic acid derivative designed for advanced chemical synthesis. This compound matters as a critical building block in modern pharmaceutical and agrochemical research, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used to construct complex heterocyclic scaffolds for new pesticides and herbicides.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional materials.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for palladium-catalyzed coupling reactions to form biaryl structures.
• Chemical Biology Probes: Utilized in the development of sensors and probes that interact with diol-containing biomolecules.
• Process Chemistry: Employed in route scouting and scale-up for the commercial manufacturing of fine chemicals.

Basic Information

Item	Detail
Product Name	3-Chloro-5-(Ethylcarbamoyl)Phenylboronic Acid
CAS No.	957120-49-9
Molecular Formula	C9H11BClNO3
Molecular Weight	227.45 g/mol
Synonyms	[3-Chloro-5-(ethylaminocarbonyl)phenyl]boronic acid; 3-Chloro-5-(ethylcarbamoyl)benzeneboronic acid; 5-Borono-3-chloro-N-ethylbenzamide; (3-Chloro-5-[(ethylamino)carbonyl]phenyl)boronic acid; B-[3-Chloro-5-(ethylcarbamoyl)phenyl]boronic acid; 957120-49-9; 3-Chloro-5-carbamoylphenylboronic acid ethyl derivative
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(Ethylcarbamoyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (by titration)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.