Description

3-Chloro-5-(Piperidine-1-Carbonyl)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group for Suzuki-Miyaura cross-coupling reactions with a piperidine-carbonyl moiety that introduces specific steric and electronic properties. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including potential drug candidates and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders.
• Suzuki-Miyaura Cross-Coupling Reagent: Used to form carbon-carbon bonds for constructing biaryl and heterobiaryl structures in medicinal chemistry programs.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-piperidine motifs.
• Material Science: Serves as a monomer or functionalization agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology Probe Development: Utilized to synthesize molecules for studying biological pathways and protein-ligand interactions.
• Library Synthesis for Drug Discovery: A valuable building block for generating diverse compound libraries in high-throughput screening campaigns.

Basic Information

Product Name	3-Chloro-5-(Piperidine-1-Carbonyl)Phenylboronic Acid
CAS No.	957120-47-7
Molecular Formula	C12H15BClNO3
Molecular Weight	267.52 g/mol
Synonyms	(3-Chloro-5-(piperidine-1-carbonyl)phenyl)boronic acid; 3-Chloro-5-(1-piperidinecarbonyl)benzeneboronic acid; 3-Chloro-5-piperidin-1-ylcarbonylphenylboronic acid; 3-Chloro-5-(piperidine-1-carbonyl)benzeneboronic acid; Boronic acid, B-[3-chloro-5-(1-piperidinylcarbonyl)phenyl]-; 957120-47-7; 3-Chloro-5-(piperidinecarbonyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(Piperidine-1-Carbonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with high-purity research-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.