Description

6-Bromo-2-Chloro-3-Methylphenylboronic Acid CAS NO 957120-28-4 is a high-purity, multi-substituted phenylboronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its unique halogenated structure, which enables precise cross-coupling reactions for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated phenyl ring for bioactivity.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and conductive polymers, where specific substitution patterns are required.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors for biochemical research and diagnostics.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CROs/CMOs serving the global life sciences industry.

Basic Information

Product Name	6-Bromo-2-Chloro-3-Methylphenylboronic Acid
CAS No.	957120-28-4
Molecular Formula	C7H7BBrClO2
Molecular Weight	249.30 g/mol
Synonyms	(6-Bromo-2-chloro-3-methylphenyl)boronic acid; 2-Chloro-6-bromo-3-methylbenzeneboronic acid; Boronic acid, B-(6-bromo-2-chloro-3-methylphenyl)-; 6-Bromo-2-chloro-m-tolylboronic acid; 3-Methyl-6-bromo-2-chlorophenylboronic acid; B-(6-Bromo-2-chloro-3-methylphenyl)boronic acid; 957120-28-4
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Chloro-3-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing lot-specific results are provided with every shipment. We support compliance with cGMP, ISO, and other relevant quality standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.