Description

N'-Acetyl-3-(4-Boronophenyl)Propanehydrazide is a specialized boron-containing organic compound that serves as a valuable synthetic intermediate and building block. Its molecular structure, featuring both an acetyl hydrazide moiety and a boronic acid/ester group, makes it a versatile reagent for cross-coupling reactions and bioconjugation strategies. This chemical is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting enzymes via boronic acid-based protease inhibition.
• Suzuki-Miyaura Cross-Coupling: Serves as an organoboron reagent for forming carbon-carbon bonds in the construction of complex biaryl structures common in active pharmaceutical ingredients (APIs).
• Bioconjugation & Probe Development: Used in the design of chemical probes, diagnostic agents, and antibody-drug conjugates (ADCs) due to its reactive boronic acid group.
• Agrochemical Research: Intermediate in the development of novel herbicides and fungicides that utilize boron chemistry for enhanced activity.
• Materials Science: Precursor for synthesizing boron-doped organic semiconductors or polymers with unique electronic properties.
• Chemical Biology Tool: Employed in studying carbohydrate interactions and developing sensors, leveraging the affinity of boronic acids for diols.

Basic Information

Product Name	N'-Acetyl-3-(4-Boronophenyl)Propanehydrazide
CAS No.	957066-08-9
Molecular Formula	C11H15BN2O2
Molecular Weight	218.06 g/mol
Synonyms	3-(4-Boronophenyl)-N'-acetylpropanehydrazide; 4-(3-(2-Acetylhydrazinyl)propyl)benzeneboronic acid; N-Acetyl-3-(4-boronophenyl)propanehydrazide; 1-Acetyl-2-[3-(4-boronophenyl)propyl]hydrazine; [4-[3-(Acetylhydrazino)propyl]phenyl]boronic acid; B-[4-[3-(Acetylhydrazino)propyl]phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our N'-Acetyl-3-(4-Boronophenyl)Propanehydrazide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and elemental analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications. We support development with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Standard Grade)
Water Content (KF)	≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.