Description

2-Amino-5-(4-Boronophenyl)-1,3,4-Thiadiazole is a specialized heterocyclic organic compound featuring a unique boronic acid functional group integrated into a thiadiazole scaffold. This molecular architecture makes it a valuable key intermediate and building block in advanced synthetic chemistry, particularly for applications requiring precise molecular recognition and cross-coupling capabilities. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially for kinase inhibitors and boron neutron capture therapy (BNCT) agents.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides that leverage the boronic acid moiety for targeted activity.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as an essential boronic acid pinacol ester precursor for forming carbon-carbon bonds in complex molecule assembly.
• Materials Science & OLED Development: Employed in the creation of organic electronic materials, including electron-transport layers and emissive materials for OLED devices.
• Chemical Biology & Probe Design: Utilized in designing molecular probes and sensors that exploit boronic acid's affinity for diols, useful in carbohydrate sensing.
• Academic & Contract Research: A valuable reagent for universities and CROs conducting research in medicinal chemistry and organic synthesis methodologies.

Basic Information

Item	Details
Product Name	2-Amino-5-(4-Boronophenyl)-1,3,4-Thiadiazole
CAS No.	957034-52-5
Molecular Formula	C8H8BN3O2S
Molecular Weight	221.04 g/mol
Synonyms	5-(4-Boronophenyl)-1,3,4-thiadiazol-2-amine; 2-Amino-5-(4-boronophenyl)-1,3,4-thiadiazole; 4-(2-Amino-1,3,4-thiadiazol-5-yl)benzeneboronic acid; 5-(4-Boronophenyl)-2-amino-1,3,4-thiadiazole; [4-(2-Amino-1,3,4-thiadiazol-5-yl)phenyl]boronic acid; B-[4-(2-Amino-1,3,4-thiadiazol-5-yl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(4-Boronophenyl)-1,3,4-Thiadiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and elemental analysis to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.