Description

(2S)-2-[(4,7-Dimethoxy-1H-Indol-2-Yl)Formamido]-2-Phenylacetic Acid is a high-purity chiral indole derivative of significant interest in advanced pharmaceutical synthesis. This compound matters as a sophisticated building block for medicinal chemistry research, enabling the development of novel therapeutic agents. It is primarily needed by R&D laboratories and pharmaceutical manufacturers focused on creating new drug candidates, particularly in areas requiring complex, stereochemically defined molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a building block for constructing complex indole-based molecules for biological screening and structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Serves as a substrate or reagent in catalytic asymmetric reactions due to its defined stereocenter.
• Reference Standard: Employed as an analytical standard for method development and quality control in pharmaceutical analysis.
• Peptidomimetic Development: The phenylglycine and formamido moieties make it valuable for designing peptide-like drug molecules.
• Chemical Biology Probes: Utilized in the synthesis of probes for studying biological pathways and target engagement.

Basic Information

Product Name	(2S)-2-[(4,7-Dimethoxy-1H-Indol-2-Yl)Formamido]-2-Phenylacetic Acid
CAS No.	956951-92-1
Molecular Formula	C19H18N2O5
Molecular Weight	354.36 g/mol
Synonyms	N-[(4,7-Dimethoxy-1H-indol-2-yl)carbonyl]-L-phenylglycine; (S)-2-((4,7-Dimethoxy-1H-indole-2-carboxamido)-2-phenylacetic acid; L-Phenylglycine, N-(4,7-dimethoxy-1H-indol-2-ylcarbonyl)-; 956951-92-1; (S)-2-(4,7-Dimethoxy-1H-indole-2-carboxamido)-2-phenylacetic acid; (2S)-2-[[(4,7-Dimethoxy-1H-indol-2-yl)carbonyl]amino]-2-phenylacetic acid
EINECS	Contact for details

Quality Control

Our (2S)-2-[(4,7-Dimethoxy-1H-Indol-2-Yl)Formamido]-2-Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.