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(2S)-2-[[6,7-Dimethoxy-1-(4-Methoxyphenyl)-3,4-Dihydro-1H-Isoquinoline-2-Carbonyl]Amino]Propanoic Acid CAS NO 956935-85-6


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CAS No.:956935-85-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2S)-2-[[6,7-Dimethoxy-1-(4-Methoxyphenyl)-3,4-Dihydro-1H-Isoquinoline-2-Carbonyl]Amino]Propanoic Acid is a high-purity, non-natural amino acid derivative featuring a complex isoquinoline scaffold. This compound is of significant value as a key chiral building block and advanced pharmaceutical intermediate in modern synthetic chemistry. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly for central nervous system (CNS) targets and enzyme inhibition studies.

Application

  • Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, especially those targeting neurological pathways.
  • Chiral Building Block: Used in asymmetric synthesis to introduce specific stereochemistry into larger, biologically active molecules.
  • Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
  • Biochemical Tool Compound: Utilized in vitro and in vivo to study enzyme function and receptor binding mechanisms.
  • Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
  • Peptidomimetic Synthesis: Incorporated into peptide analogs to enhance stability, bioavailability, and target specificity.

Basic Information

Product Name (2S)-2-[[6,7-Dimethoxy-1-(4-Methoxyphenyl)-3,4-Dihydro-1H-Isoquinoline-2-Carbonyl]Amino]Propanoic Acid
CAS No. 956935-85-6
Molecular Formula C22H26N2O6
Molecular Weight 414.46 g/mol
Synonyms (S)-2-((6,7-Dimethoxy-1-(4-methoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbonyl)amino)propanoic acid; L-Alanine, N-[(1S)-6,7-dimethoxy-1-(4-methoxyphenyl)-3,4-dihydro-2(1H)-isoquinolinecarbonyl]-; N-[(1S)-6,7-Dimethoxy-1-(4-methoxyphenyl)-1,2,3,4-tetrahydro-2-isoquinolinylcarbonyl]-L-alanine; (S)-N-(6,7-Dimethoxy-1-(4-methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)alanine; 956935-85-6; Isoquinoline-2-carboxamide derivative
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Quality Control

Our (2S)-2-[[6,7-Dimethoxy-1-(4-Methoxyphenyl)-3,4-Dihydro-1H-Isoquinoline-2-Carbonyl]Amino]Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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