Description

1-Ethyl-3-Methyl-4-Nitro-1H-Pyrazole-5-Carboxylic Acid Ethyl Ester is a high-purity, functionalized pyrazole derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile nitro-substituted heterocyclic scaffold for constructing complex molecules with targeted biological or material properties. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Used in the creation of specialty polymers, ligands for metal-organic frameworks (MOFs), and organic electronic materials.
• Chemical Biology Probe Development: Serves as a core structure for designing enzyme inhibitors and molecular probes to study biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	1-Ethyl-3-Methyl-4-Nitro-1H-Pyrazole-5-Carboxylic Acid Ethyl Ester
CAS No.	956935-26-5
Molecular Formula	C9H13N3O4
Molecular Weight	227.22 g/mol
Synonyms	Ethyl 1-Ethyl-3-methyl-4-nitro-1H-pyrazole-5-carboxylate; 4-Nitro-1-ethyl-3-methyl-1H-pyrazole-5-carboxylic acid ethyl ester; 1H-Pyrazole-5-carboxylic acid, 1-ethyl-3-methyl-4-nitro-, ethyl ester; EMNPCE; 956935-26-5; 1-Ethyl-3-methyl-4-nitropyrazole-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 1-Ethyl-3-Methyl-4-Nitro-1H-Pyrazole-5-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects requiring compliance with ICH guidelines and can supply material suitable for use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.