Description

(3R)-2-Acetyl-1-Phenyl-2,3,4,9-Tetrahydro-1H-β-Carboline-3-Carboxylic Acid is a high-purity, chiral β-carboline derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a sophisticated building block for the development of novel bioactive molecules, particularly those targeting neurological and oncological pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex heterocyclic libraries.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential drug candidates, especially those with β-carboline or tetrahydroisoquinoline scaffolds.
• Medicinal Chemistry Research: Used as a core structure for structure-activity relationship (SAR) studies and the design of new chemical entities with targeted biological activity.
• Asymmetric Synthesis: Valuable chiral building block for constructing complex, enantiomerically pure molecules in academic and industrial R&D settings.
• Biochemical Tool Compound: Potential use in biochemical assays to study enzyme inhibition or receptor binding mechanisms related to its structural class.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions for clinical trial material.
• Reference Standard: High-purity material suitable for use as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(3R)-2-Acetyl-1-Phenyl-2,3,4,9-Tetrahydro-1H-β-Carboline-3-Carboxylic Acid
CAS No.	956923-54-9
Molecular Formula	C21H20N2O3
Molecular Weight	348.40 g/mol
Synonyms	(3R)-2-Acetyl-1-phenyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid; (R)-2-Acetyl-1-phenyl-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid; 1H-β-Carboline-3-carboxylic acid, 2-acetyl-1,2,3,4-tetrahydro-1-phenyl-, (3R)-; (R)-2-Acetyl-1-phenyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid; 956923-54-9; (3R)-ATPC; (R)-ATPC
EINECS	Contact for details

Quality Control

Our (3R)-2-Acetyl-1-Phenyl-2,3,4,9-Tetrahydro-1H-β-Carboline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.