Description

1-(4-Butyl-Phenyl)-5-(4-Chloro-Phenyl)-3-Methyl-1H-Pyrazole-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it offers a critical building block for medicinal chemistry research and development, enabling the creation of novel therapeutic agents with precise structural control. Pharmaceutical manufacturers and R&D laboratories need this high-quality intermediate to ensure the reliability, scalability, and regulatory compliance of their synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel pyrazole-based active pharmaceutical ingredients (APIs) for therapeutic applications.
• Medicinal Chemistry Research: Used in drug discovery and development programs for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Serves as a building block for developing advanced crop protection agents and pesticides with specific biological activity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science Research: Investigated as a monomer or functional component for creating specialty polymers with unique thermal or optical properties.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	1-(4-Butyl-Phenyl)-5-(4-Chloro-Phenyl)-3-Methyl-1H-Pyrazole-4-Carboxylic Acid
CAS No.	956786-73-5
Molecular Formula	C21H21ClN2O2
Molecular Weight	368.86 g/mol
Synonyms	1-(4-Butylphenyl)-5-(4-chlorophenyl)-3-methyl-1H-pyrazole-4-carboxylic acid; 4-Butyl-1-(4-chlorophenyl)-3-methyl-1H-pyrazole-5-carboxylic acid (alternative numbering); 1H-Pyrazole-4-carboxylic acid, 1-(4-butylphenyl)-5-(4-chlorophenyl)-3-methyl-; 956786-73-5; 1-(4-n-Butylphenyl)-5-(4-chlorophenyl)-3-methylpyrazole-4-carboxylic acid; Pyrazole carboxylic acid derivative (C21H21ClN2O2); 5-(4-Chlorophenyl)-1-(4-butylphenyl)-3-methyl-1H-pyrazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(4-Butyl-Phenyl)-5-(4-Chloro-Phenyl)-3-Methyl-1H-Pyrazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided for every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.