Description

Isoquinoline, 7-Bromo-1-Chloro-4-Fluoro- is a high-purity, multi-halogenated isoquinoline derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its precise halogen substitution pattern makes it an invaluable building block for constructing complex molecular architectures with targeted electronic and steric properties. This compound is primarily sought by research institutions and pharmaceutical developers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Building block for creating organic semiconductors, liquid crystals, and photoactive materials due to its electron-deficient aromatic core.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Catalyst Ligand Synthesis: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	Isoquinoline, 7-Bromo-1-Chloro-4-Fluoro-
CAS No.	956700-16-6
Molecular Formula	C9H4BrClFN
Molecular Weight	260.49 g/mol
Synonyms	7-Bromo-1-chloro-4-fluoroisoquinoline; 1-Chloro-7-bromo-4-fluoroisoquinoline; 4-Fluoro-7-bromo-1-chloroisoquinoline; 956700-16-6; Isoquinoline, 1-chloro-7-bromo-4-fluoro-; 7-Bromo-1-chloro-4-fluoro-isoquinoline; 1-Chloro-4-fluoro-7-bromoisoquinoline
EINECS	Contact for details

Quality Control

Every batch of Isoquinoline, 7-Bromo-1-Chloro-4-Fluoro- is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.