Description

Methyl 2-Isocyanato-5-Methylthiophene-3-Carboxylate is a high-purity, heterocyclic building block featuring both an isocyanate and an ester functional group on a thiophene scaffold. This compound is a critical intermediate for the synthesis of advanced pharmaceutical agents and agrochemicals, enabling the construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of small molecule drugs, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the thiophene core for bioactivity.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialty polymers, coatings, and adhesives with tailored properties.
• Chemical Research (R&D): An essential reagent in academic and industrial laboratories for exploring new heterocyclic chemistry and developing novel synthetic methodologies.
• Ligand & Catalyst Development: Used to create novel ligands for metal complexes and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Methyl 2-Isocyanato-5-Methylthiophene-3-Carboxylate
CAS No.	956576-57-1
Molecular Formula	C8H7NO3S
Molecular Weight	197.21 g/mol
Synonyms	Methyl 5-Methyl-2-isocyanatothiophene-3-carboxylate; 5-Methyl-2-isocyanatothiophene-3-carboxylic acid methyl ester; 2-Isocyanato-5-methylthiophene-3-carboxylic acid methyl ester; Thiophene-3-carboxylic acid, 2-isocyanato-5-methyl-, methyl ester; Methyl (2-isocyanato-5-methyl-3-thienyl)carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2-Isocyanato-5-Methylthiophene-3-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global customer base in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.