Description

Mavatrep CAS NO 956274-94-5 is a high-purity, non-steroidal anti-inflammatory drug (NSAID) compound belonging to the TRPV1 antagonist class. It is valued for its potent and selective mechanism of action in targeting pain pathways, offering significant research and development potential. This compound is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on developing novel analgesic and anti-inflammatory therapeutics.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of new pain management drugs.
• Analgesic Drug Discovery: A critical tool compound for studying TRPV1 receptor pharmacology and screening for next-generation analgesic agents.
• Preclinical Studies: Used in in vitro and in vivo models to investigate efficacy, pharmacokinetics, and safety profiles of TRPV1-targeting therapies.
• Chemical Synthesis: Serves as a sophisticated building block for the synthesis of novel chemical entities and analogs in medicinal chemistry programs.
• Biomolecular Research: Employed in studies exploring neurogenic inflammation, chronic pain conditions, and thermal sensation pathways.

Basic Information

Product Name	Mavatrep
CAS No.	956274-94-5
Molecular Formula	C24H21F3N2O3S
Molecular Weight	474.50 g/mol
Synonyms	Mavatrep; JNJ-39439335 (mavatrep); (R)-N-(4-(6-(4-(Trifluoromethyl)phenyl)pyridazin-3-yl)oxy)chroman-7-yl)methanesulfonamide; JNJ 39439335; UNII-9J97361Y2H; 9J97361Y2H; (R)-N-[[4-[[6-[4-(Trifluoromethyl)phenyl]-3-pyridazinyl]oxy]-2H-1-benzopyran-7-yl]]methanesulfonamide
EINECS	Contact for details

Quality Control

Our Mavatrep is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and rigorous control of residual solvents and impurities to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.