Description

(+-)-Methadone Hydrochloride--Dea CAS NO 125-56-4 is a synthetic opioid analgesic and a key pharmaceutical active ingredient. It is a critical compound for the production of controlled medication used in pain management and addiction treatment programs. This high-purity substance is essential for pharmaceutical manufacturers, analytical reference standard producers, and research institutions developing therapeutic protocols.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of methadone-based medications for severe pain management.
• Opioid Dependence Treatment: A cornerstone component in Medication-Assisted Treatment (MAT) programs for opioid use disorder.
• Analytical Reference Standard: Used in forensic, clinical, and pharmaceutical laboratories for qualitative and quantitative analysis (e.g., HPLC, GC-MS).
• Clinical Research & Development: Serves as a key reagent in pharmacological studies and the development of new analgesic formulations.
• Controlled Substance Manufacturing: Supplied to licensed facilities for the production of DEA-scheduled pharmaceutical products.

Basic Information

Product Name	(+-)-Methadone Hydrochloride--Dea CAS NO 125-56-4
CAS No.	125-56-4
Molecular Formula	C21H27NO • HCl
Molecular Weight	345.91 g/mol
Synonyms	Methadone HCl; (±)-Methadone Hydrochloride; DL-Methadone Hydrochloride; 6-(Dimethylamino)-4,4-diphenyl-3-heptanone Hydrochloride; Amidon Hydrochloride; Phenadone Hydrochloride; Heptadon Hydrochloride; EINECS 204-754-5
EINECS	204-754-5

Quality Control

Our (+-)-Methadone Hydrochloride is manufactured under strict quality systems to ensure it meets the exacting standards required for pharmaceutical and analytical use. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant Good Manufacturing Practice (GMP) principles where applicable, and the product is suitable for use as a pharmaceutical reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. Keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.