Description

Dihydronormorphine is a semi-synthetic opioid alkaloid of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate and reference standard for the synthesis and analytical study of more complex opioid derivatives and their metabolites. It is essential for researchers and manufacturers in the pharmaceutical and forensic science industries who require high-purity, well-characterized chemical entities for method development, quality control, and investigative studies.

Application

• Pharmaceutical Intermediate: A key precursor in the research-scale synthesis of specialized opioid analgesics and antagonist compounds.
• Analytical Reference Standard: Used for the identification, method validation, and quantification in High-Performance Liquid Chromatography (HPLC), Gas Chromatography-Mass Spectrometry (GC-MS), and other analytical techniques.
• Metabolite Studies: Employed in pharmacological and toxicological research to study the metabolic pathways and biotransformation of related opioid substances.
• Forensic Analysis: Serves as a certified reference material for the accurate analysis of controlled substances in forensic laboratories.
• Biochemical Research: Utilized in receptor binding assays and studies investigating the structure-activity relationships (SAR) of opioid ligands.

Basic Information

Product Name	Dihydronormorphine
CAS No.	1421-13-2
Molecular Formula	C16H21NO3
Molecular Weight	275.34 g/mol
Synonyms	Dihydronormorphine; 4,5α-Epoxy-3-hydroxy-17-methylmorphinan-6-one; 7,8-Dihydronormorphine; Normorphinan-6-one, 4,5-epoxy-3-hydroxy-17-methyl-; Dihydronorcodeinone
EINECS	Contact for details

Quality Control

Our Dihydronormorphine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant guidelines for reference standards, and specifications can be provided to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.