Description

Methyl 3-Methyl-5-Nitrothiophene-2-Carboxylate is a high-purity, specialized heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its functionalized thiophene scaffold, which serves as a versatile precursor for the development of complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), functional materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for constructing thiophene-containing drug candidates, particularly in areas like kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that leverage the thiophene moiety for bioactivity.
• Material Science Research: Serves as a precursor for conjugated polymers and organic electronic materials due to the electron-withdrawing nitro and ester groups on the thiophene ring.
• Chemical Biology: Employed in the synthesis of molecular probes and labeled compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, functionalized heterocyclic architectures.

Basic Information

Product Name	Methyl 3-Methyl-5-Nitrothiophene-2-Carboxylate
CAS No.	956118-35-7
Molecular Formula	C7H7NO4S
Molecular Weight	201.20 g/mol
Synonyms	Methyl 3-methyl-5-nitro-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 3-methyl-5-nitro-, methyl ester; 3-Methyl-5-nitrothiophene-2-carboxylic acid methyl ester; 5-Nitro-3-methylthiophene-2-carboxylic acid methyl ester; Methyl 5-nitro-3-methylthiophene-2-carboxylate; 956118-35-7
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Methyl-5-Nitrothiophene-2-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.