Description

3-[(4-Methoxyphenyl)Methoxy]Pyridine-5-Boronic Acid Pinacol Ester is a high-value, organoboron building block used in advanced organic synthesis, specifically in cross-coupling reactions. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands for catalysis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds between aromatic rings, essential for constructing complex biaryl structures found in many drug candidates.
• Pharmaceutical Intermediate: Serves as a versatile building block in the synthesis of potential therapeutic agents, including kinase inhibitors and other small molecule drugs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific biphenyl or heterobiaryl motifs.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs (Organic Light-Emitting Diodes) and semiconductors, where precise molecular architecture is crucial.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological processes and target engagement.

Basic Information

Product Name	3-[(4-Methoxyphenyl)Methoxy]Pyridine-5-Boronic Acid Pinacol Ester
CAS No.	956034-20-1
Molecular Formula	C19H24BNO4
Molecular Weight	341.21 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-[(4-methoxyphenyl)methoxy]pyridine; 3-[(4-Methoxyphenyl)Methoxy]-5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-(4-Methoxybenzyloxy)pyridine-5-boronic acid pinacol ester; (3-((4-Methoxybenzyl)oxy)pyridin-5-yl)boronic acid pinacol ester; 956034-20-1; Boronic acid, B-[3-[[(4-methoxyphenyl)methoxy]phenyl]-5-, 1,1-dimethylethyl ester; Pyridine-5-boronic acid, 3-[(4-methoxyphenyl)methoxy]-, pinacol ester
EINECS	Contact for details

Quality Control

Our 3-[(4-Methoxyphenyl)Methoxy]Pyridine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance in sensitive cross-coupling applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and easily oxidized nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.